CRNN antibody (AA 380-460)

Catalog No. ABIN7228064

This Rabbit Polyclonal antibody specifically detects CRNN in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for CRNN antibody (AA 380-460) (ABIN7228064)

Target: CRNN (Cornulin (CRNN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRNN antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CRNN Antibody

Binding Specificity: AA 380-460

Purpose: Rabbit Anti-CRNN Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CRNN protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CRNN protein at AA range: 380-460

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CRNN

Target: CRNN (Cornulin (CRNN))

Alternative Name: CRNN

Background: Cornulin, 53 kDa putative calcium-binding protein, 53 kDa squamous epithelial-induced stress protein, 58 kDa heat shock protein, Squamous epithelial heat shock protein 53, Tumor-related proteinCRNN encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein CRNN contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. CRNN, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.

Molecular Weight: 54kD

Gene ID: 49860

UniProt: Q9UBG3