FTO antibody

Catalog No. ABIN1169073

The Mouse Monoclonal anti-FTO antibody (Clone AG103) (ABIN1169073) specifically detects FTO in WB, IHC, ELISA and IP. The antibody is reactive with Human samples.

Quick Overview for FTO antibody (ABIN1169073)

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTO antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Clone: AG103

Product Details anti-FTO Antibody

Purpose: anti-FTO (human), mAb (AG103)

Specificity: Recognizes human FTO.

Characteristics: Monoclonal Antibody. Recognizes human FTO. Isotype: Mouse IgG2akappa. Clone: AG103. Applications: ELISA, IHC, IP, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human FTO.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Alternative Name: FTO

Background:

Alternate Names/Synonyms: Fat Mass and Obesity-associated Protein, FATSO

Product Description: FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

UniProt: Q9C0B1