FTO antibody

Catalog No. ABIN1169074

This Mouse Monoclonal antibody specifically detects FTO in WB, IHC, ELISA and IP. It exhibits reactivity toward Mouse.

Quick Overview for FTO antibody (ABIN1169074)

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTO antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Clone: FT62-6

Product Details anti-FTO Antibody

Purpose: anti-FTO (mouse), mAb (FT62-6)

Specificity: Recognizes mouse FTO. Weakly cross-reacts with human FTO. Does not cross-react with rat FTO.

No Cross-Reactivity: Rat (Rattus)

Cross-Reactivity (Details): Weakly cross-reacts with human FTO. Does not cross-react with rat FTO.

Characteristics: Monoclonal Antibody. Recognizes mouse FTO. Weakly cross-reacts with human FTO. Does not cross-react with rat FTO. Isotype: Mouse IgG1kappa. Clone: FT62-6. Applications: ELISA, IHC, IP, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human FTO.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Alternative Name: FTO

Background:

Alternate Names/Synonyms: Fat Mass and Obesity-associated Protein, FATSO

Product Description: FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

UniProt: Q8BGW1