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TICAM2 antibody (AA 2-29)

TICAM2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1169199
  • Target See all TICAM2 Antibodies
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Binding Specificity
    • 8
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-29
    Reactivity
    • 49
    • 17
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 47
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 51
    Polyclonal
    Conjugate
    • 29
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TICAM2 antibody is un-conjugated
    Application
    • 43
    • 24
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    Recognizes human TRAM.
    Cross-Reactivity
    Human
    Immunogen
    Synthetic peptide corresponding to aa 2-29 (G2IGKSKINSCPLSLSWGKRHSVDTSPGY29) of human TRAM.
    Top Product
    Discover our top product TICAM2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Neat serum containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Expiry Date
    12 months
  • Aksoy, Albarani, Nguyen, Laes, Ruelle, De Wit, Willems, Goldman, Goriely: "Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." in: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).

  • Target
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Alternative Name
    TRAM (TICAM2 Products)
    Synonyms
    MyD88-4 antibody, TICAM-2 antibody, TIRAP3 antibody, TIRP antibody, TRAM antibody, B430113A10 antibody, Tirp antibody, Trif antibody, toll like receptor adaptor molecule 2 antibody, toll-like receptor adaptor molecule 2 antibody, TICAM2 antibody, Ticam2 antibody
    Background
    TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas.
    UniProt
    Q86XR7
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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