DLL1 antibody

Catalog No. ABIN1169246

There is 1 publication for this product available. The Rat Monoclonal anti-DLL1 antibody is suitable to detect DLL1 in samples from Mouse. It has been validated for FACS and ICC.

Quick Overview for DLL1 antibody (ABIN1169246)

Target: DLL1 (delta-Like 1 (DLL1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This DLL1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 30B11-1

Product Details anti-DLL1 Antibody

Purpose: anti-DLL1 (mouse), mAb (30B11.1)

Specificity: Recognizes mouse DLL1.

Characteristics: Monoclonal Antibody. Recognizes mouse DLL1. Isotype: Rat IgG2akappa. Clone: 30B11.1. Applications: FACS, ICC. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. It blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Purity: >95 % (SDS-PAGE)

Immunogen: Recombinant mouse DLL1:Fc.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

References for anti-DLL1 antibody (ABIN1169246)

Fiorini, Ferrero, Merck, Favre, Pierres, Luther, MacDonald: "Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 12, pp. 8199-203, (2008) (PubMed).

Target Details for DLL1

Target: DLL1 (delta-Like 1 (DLL1))

Alternative Name: DLL1

Background:

Alternate Names/Synonyms: Delta-like Protein 1, Delta 1

Product Description: The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. It blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.

UniProt: Q61483

Pathways: Notch Signaling, Stem Cell Maintenance