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DLL4 antibody

DLL4 Reactivity: Mouse FACS, ICC Host: Rat Monoclonal 9A1-5 unconjugated
Catalog No. ABIN1169261
  • Target See all DLL4 Antibodies
    DLL4 (delta-Like 4 (DLL4))
    Reactivity
    • 49
    • 35
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 55
    • 14
    • 7
    • 1
    • 1
    Rat
    Clonality
    • 57
    • 21
    Monoclonal
    Conjugate
    • 45
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DLL4 antibody is un-conjugated
    Application
    • 40
    • 28
    • 13
    • 13
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificity
    Recognizes mouse DLL4.
    Cross-Reactivity
    Mouse (Murine)
    Purification
    Purified from concentrated hybridoma tissue culture supernatant.
    Purity
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant mouse DLL4:Fc.
    Clone
    9A1-5
    Isotype
    IgG1
    Top Product
    Discover our top product DLL4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Expiry Date
    12 months
  • Fiorini, Ferrero, Merck, Favre, Pierres, Luther, MacDonald: "Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 12, pp. 8199-203, (2008) (PubMed).

  • Target
    DLL4 (delta-Like 4 (DLL4))
    Alternative Name
    DLL4 (DLL4 Products)
    Synonyms
    hdelta2 antibody, Delta4 antibody, si:ch211-244p18.5 antibody, zgc:136596 antibody, delta like canonical Notch ligand 4 antibody, delta-like 4 (Drosophila) antibody, DLL4 antibody, Dll4 antibody, dll4 antibody
    Background
    The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
    UniProt
    Q9JI71
    Pathways
    Notch Signaling
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