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PIDD antibody
PIDD
Reactivity: Mouse
WB
Host: Mouse
Monoclonal
Lise-1
unconjugated
Product Details anti-PIDD Antibody
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Target
See all PIDD Antibodies
PIDD
(P53-Induced Death Domain Protein (PIDD))
Reactivity
All reactivities for PIDD antibodies
Mouse
Host
All hosts for PIDD antibodies
Mouse
Clonality
All clonalities for PIDD antibodies
Monoclonal
Conjugate
All conjugates for PIDD antibodies
This PIDD antibody is un-conjugated
Application
All applications for PIDD antibodies
Western Blotting (WB)
Specificity
Recognizes mouse PIDD.
Cross-Reactivity
Mouse (Murine)
Purification
Purified from concentrated hybridoma tissue culture supernatant.
Purity
>95 % (SDS-PAGE)
Immunogen
Mouse PIDD (Death Domain).
Clone
Lise-1
Isotype
IgG2b
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
Target Details for PIDD
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Target
PIDD
(P53-Induced Death Domain Protein (PIDD))
Alternative Name
PIDD (PIDD Products )
Background
PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
UniProt
Q9ERV7
Pathways
p53 Signaling , Caspase Cascade in Apoptosis , Positive Regulation of Endopeptidase Activity
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