Calreticulin antibody

Catalog No. ABIN1169307

The Mouse Monoclonal anti-Calreticulin antibody (Clone CR213-2AG) (ABIN1169307) specifically detects Calreticulin in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Calreticulin antibody (ABIN1169307)

Target: Calreticulin (CALR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calreticulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: CR213-2AG

Product Details anti-Calreticulin Antibody

Purpose: anti-Calreticulin (human), mAb (CR213-2AG)

Specificity: Recognizes human calreticulin.

Characteristics: Monoclonal Antibody. Recognizes human calreticulin. Isotype: Mouse IgG1kappa. Clone: CR213-2AG. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human calreticulin.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for Calreticulin

Target: Calreticulin (CALR)

Alternative Name: Calreticulin

Background:

Alternate Names/Synonyms: CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60

Product Description: Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response