FGF19 antibody

Catalog No. ABIN1169398

This Mouse Monoclonal antibody specifically detects FGF19 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for FGF19 antibody (ABIN1169398)

Target: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: FG98-6

Product Details anti-FGF19 Antibody

Purpose: anti-FGF-19 (human), mAb (FG98-6)

Specificity: Recognizes human FGF-19. Detects a band of ~25 kDa by Western blot.

Characteristics: Monoclonal Antibody. Recognizes human FGF-19. Detects a band of ~25 kDa by Western blot. Isotype: Mouse IgG2bkappa. Clone: FG98-6. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human FGF-19.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for FGF19

Target: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Alternative Name: FGF-19

Background:

Alternate Names/Synonyms: Fibroblast Growth Factor 19

Product Description: FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

UniProt: O95750

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway