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CD4 antibody

CD4 Reactivity: Human FACS, Func Host: Mouse Monoclonal RPA-T4 unconjugated
Catalog No. ABIN1177369
  • Target See all CD4 Antibodies
    CD4
    Reactivity
    • 324
    • 200
    • 115
    • 48
    • 24
    • 20
    • 19
    • 18
    • 17
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 332
    • 146
    • 110
    • 3
    • 3
    • 1
    Mouse
    Clonality
    • 450
    • 137
    • 5
    Monoclonal
    Conjugate
    • 201
    • 70
    • 62
    • 44
    • 36
    • 12
    • 11
    • 10
    • 10
    • 9
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD4 antibody is un-conjugated
    Application
    • 474
    • 190
    • 125
    • 102
    • 92
    • 71
    • 69
    • 42
    • 39
    • 34
    • 31
    • 28
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Brand
    BD Pharmingen™
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Clone
    RPA-T4
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD4 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Target
    CD4
    Alternative Name
    CD4 (CD4 Products)
    Background
    The RPA-T4 clone reacts with CD4, a 59 kDa single-chain transmembrane glycoprotein [receptor for human immunodeficiency virus (HIV)] present on T-helper/inducer cell populations. This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. CD4 is also present in low density on peripheral blood monocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation. This antibody is capable of blocking mixed-lymphocyte reaction (MLR).
    Pathways
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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