MME antibody (FITC)

Catalog No. ABIN119106

The FITC-conjugated Mouse Monoclonal anti-MME antibody (Clone SN5c) (ABIN119106) specifically detects MME in FACS. The antibody is reactive with Human samples.

Quick Overview for MME antibody (FITC) (ABIN119106)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MME antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: SN5c

Product Details anti-MME Antibody (FITC)

Specificity: This antibody recognizes the CD10 cell surface antigen.

Purification: Affinity Chromatography on Protein G

Immunogen: Partially purified cell membrane antigens from fresh leukemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse PS/NS1/1-Ag4-1 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10 / Neprilysin

Target Type: Chemical

Background: CD10 is a 100kD glycoprotein expressed by acute lymphoblastic leukaemia cells and by peripheral blood granulocytes. CD10 is also known as the Common Acute Lymphoblastic Leukaemia Antigen (CALLA).Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11

Gene ID: 4311

NCBI Accession: NP_000893

UniProt: P08473

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration