CD11b antibody

Catalog No. ABIN119464

This Mouse Monoclonal antibody specifically detects CD11b in FACS and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for CD11b antibody (ABIN119464)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD11b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ED7

Product Details anti-CD11b Antibody

Purification: Affinity chromatography on Protein A

Immunogen: Rat spleen cell homogenate. Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0 Ag-14 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry. Immunohistochemistry on frozen sections: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: CD11b

Background: The antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules (CD11b/CD18).Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor

Gene ID: 10116

UniProt: Q63001

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation