Integrin Alpha2b antibody (FITC)
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- Target See all Integrin Alpha2b (CD41) Antibodies
- Integrin Alpha2b (CD41)
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This Integrin Alpha2b antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Specificity
- This antibody recognises the integrin alpha IIb subunit CD41.
- Purification
- Protein G affinity chromatography
- Clone
- MWReg30
- Isotype
- IgG1
- Top Product
- Discover our top product CD41 Primary Antibody
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- Application Notes
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Flow cytometry: use 10 μL of neat - 1/10 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo . We recommend the use of ABIN119839 for use in functional studies. - Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide and 1 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Regulation of triggering receptor expressed on myeloid cells 1 expression on mouse inflammatory monocytes." in: Immunology, Vol. 128, Issue 2, pp. 185-95, (2009) (PubMed).
: "Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3." in: Blood, Vol. 108, Issue 5, pp. 1509-14, (2006) (PubMed).
: "
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Regulation of triggering receptor expressed on myeloid cells 1 expression on mouse inflammatory monocytes." in: Immunology, Vol. 128, Issue 2, pp. 185-95, (2009) (PubMed).
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- CD41 / ITGA2B (CD41 Products)
- Background
- CD41 is expressed on platelets and megakaryocytes and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
- Gene ID
- 16399
- NCBI Accession
- NP_034705
- UniProt
- Q9QUM0
- Pathways
- Integrin Complex
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