Integrin Alpha2b antibody
-
- Target See all Integrin Alpha2b (CD41) Antibodies
- Integrin Alpha2b (CD41)
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This Integrin Alpha2b antibody is un-conjugated
-
Application
- Flow Cytometry (FACS)
- Purification
- Protein-A affinity chromatography
- Purity
- > 95 % pure (by SDS-PAGE)
- Immunogen
- Leukocytes of patient suffering from LGL-type leukaemia
- Clone
- MEM-06
- Isotype
- IgG1
- Top Product
- Discover our top product CD41 Primary Antibody
-
-
- Application Notes
-
Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
-
Store the antibody at 2 - 8 °C up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - Expiry Date
- 12 months
-
- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- CD41 / ITGA2B (CD41 Products)
- Background
- CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, b) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
- UniProt
- P08514
- Pathways
- Integrin Complex
-