CD41, CD61 antibody

Catalog No. ABIN120593

The Mouse Monoclonal anti-CD41, CD61 antibody has been validated for FACS, IP, EIA and IHC (fro). It is suitable to detect CD41, CD61 in samples from Cow.

Quick Overview for CD41, CD61 antibody (ABIN120593)

Target: CD41, CD61 (CD41,CD61)

Reactivity: Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD41, CD61 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: IVA30

Product Details anti-CD41, CD61 Antibody

Purification: Affinity Chromatography on Protein A .

Immunogen: Bovine trombocytes

Isotype: IgG2

Application Details

Application Notes: Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Frozen Sections. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM Sodium Azide as preservative, approx. pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CD41, CD61

Target: CD41, CD61 (CD41,CD61)

Background: CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIba (heavy chain, 120 kDa) and GPIIbb (light chain, 23 kDa). CD61 non-covalently associates with CD41. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes, the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT).Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb

UniProt: P08514