Geminin antibody (N-Term)

Catalog No. ABIN121183

This Mouse Monoclonal antibody specifically detects Geminin in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Geminin antibody (N-Term) (ABIN121183)

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Geminin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 2H7

Product Details anti-Geminin Antibody

Binding Specificity: AA 1-209, N-Term

Specificity: This antibody is specific for Geminin.

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human Geminin (aa 1-209) purified from E. coli

Isotype: IgG1

Application Details

Application Notes: Western blot (1:500 - 1:1,000, recommended starting dilution 1:500). ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for Geminin

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Alternative Name: Geminin

Background: Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.Synonyms: GMNN

Gene ID: 51053

UniProt: O75496

Pathways: EGFR Signaling Pathway, DNA Replication