CD40 Ligand antibody

Catalog No. ABIN121931

The Goat Polyclonal anti-CD40 Ligand antibody is suitable to detect CD40 Ligand in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for CD40 Ligand antibody (ABIN121931)

Target: CD40 Ligand (CD40LG)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CD40 Ligand antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CD40 Ligand Antibody

Specificity: This antibody is specific for the soluble form of human CD154, also designated CD40L (sCD40 Ligand), a member of the TNF receptor superfamily, comprising the full-length of the TNF homologous region of CD154.

Purification: Affinity chromatography

Immunogen: Recombinant human soluble CD154

Application Details

Application Notes: ELISA (direct ELISA, 0.5 μg/mL). Western blot (0.1 - 0.2 μg).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.1 mL distilled water.

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline pH 7.4, containing no preservatives

Preservative: Without preservative

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2 - 8 °C and reconstituted (undiluted) at -20 °C. Avoid repeated freezing and thawing. For long term storage the addition of 0.09 % sodium azide is recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: One year from despatch.Reconstitution: Restore with 0.1 ml distilled water..

Expiry Date: 12 months

Target Details for CD40 Ligand

Target: CD40 Ligand (CD40LG)

Alternative Name: CD154 / CD40L

Background: CD154 is expressed predominantly on activated CD4+ T lymphocytes, and acts as a costimulatory molecule in B cell differentiation/proliferation, immunoglobulin switching and germinal centre formation, through interaction with the CD40 receptor on B cells, and cytokines secreted by activated T cells.Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5

Gene ID: 959

UniProt: P29965

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints