GPR109B antibody

Catalog No. ABIN122203

Product Details anti-GPR109B Antibody

Target: GPR109B (HCAR3) (Hydroxycarboxylic Acid Receptor 3 (HCAR3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR109B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: Reacts with G Protein-Coupled Receptor HM74 (family: GPCR, subfamily: Nicotinic Acid)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunocytochemistry. Immunohistochemistry on formalin fixed paraffin embedded tissues: 19-38 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for GPR109B

Target: GPR109B (HCAR3) (Hydroxycarboxylic Acid Receptor 3 (HCAR3))

Alternative Name: Nicotinic Acid Receptor 2 (HCAR3 Products)

Synonyms: GPR109B antibody, HCA3 antibody, HM74 antibody, PUMAG antibody, Puma-g antibody, NIACR2 antibody, hm74 antibody, niacr2 antibody, hydroxycarboxylic acid receptor 3 antibody, HCAR3 antibody, hcar3 antibody

Background: GPR109B/HM74 is a Nicotinic Acid GPCR. HM74 expression has been reported in adipose and spleen, as well as lymphocytes and monocytes. ESTs have been isolated from adipose, blood, liver, liver/spleen, placenta, prostate, and testis libraries.Synonyms: G-protein coupled receptor 109B, GPR109B, HM74, HM74B, NIACR2, Niacin receptor 2

Gene ID: 8843

UniProt: P49019