Growth Hormone 1 antibody

Catalog No. ABIN126135

The Rabbit Polyclonal anti-Growth Hormone 1 antibody (ABIN126135) specifically detects Growth Hormone 1 in EIA. The antibody is reactive with Human samples.

Quick Overview for Growth Hormone 1 antibody (ABIN126135)

Target: Growth Hormone 1 (GH1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Growth Hormone 1 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-Growth Hormone 1 Antibody

Specificity: The antibody recognizes Human Growth Hormone.

Purification: Affinity Chromatography on Protein G

Immunogen: Recombinant Human GH purified by HPLC.

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with double distilled water to the desired concentration.

Buffer: 0.01 M PBS, pH 7.4

Precaution of Use: Do Not Use Sodium Azide as Preservative.

Handling Advice: Avoid repeated freezing and thawing. Dilute only prior to immediate use

Storage: 4 °C/-20 °C

Storage Comment: Store vial at 2-8 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Centrifuge product if not completely clear after standing at room temperature. This antibody is stable for one month at 2-8 °C as an undiluted liquid.

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: Somatotropin / Growth Hormone / GH1

Background: Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist. Human growth hormone (hGH) is also used as a reporter protein, because it is secreted from mammalian cells it can be assayed by ELISA on culture supernatant using antibodies to determine the level of expressionSynonyms: Growth hormone 1, HGH, Pituitary growth hormone

Gene ID: 2688

NCBI Accession: NP_000506

UniProt: P01241

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process