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LIMK2 antibody (C-Term)

LIMK2 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN127209
  • Target See all LIMK2 Antibodies
    LIMK2 (LIM Domain Kinase 2 (LIMK2))
    Binding Specificity
    • 9
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 55
    • 33
    • 31
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 46
    • 3
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 54
    • 1
    Polyclonal
    Conjugate
    • 44
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIMK2 antibody is un-conjugated
    Application
    • 46
    • 25
    • 22
    • 14
    • 10
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    The antibody detects 70 kDa LIMK2 protein. It does not cross-react with LIMK1. The antibody recognizes ~35 kDa PHAP III.
    Purification
    Affinity Purified
    Immunogen
    Synthetic peptide corresponding to the C-terminus of human LIMK2.
    Top Product
    Discover our top product LIMK2 Primary Antibody
  • Application Notes
    Western Blot: 1-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • Target
    LIMK2 (LIM Domain Kinase 2 (LIMK2))
    Alternative Name
    LIMK2 (LIMK2 Products)
    Synonyms
    xlimk2 antibody, zgc:91990 antibody, wu:fa97c09 antibody, wu:fk73e11 antibody, LIMK2 antibody, Limk2b antibody, Link2 antibody, LIMK antibody, 9430059K01 antibody, A930024P04Rik antibody, C85310 antibody, Limk2a antibody, LIM domain kinase 2 L homeolog antibody, LIM domain kinase 2 antibody, LIM motif-containing protein kinase 2 antibody, limk2.L antibody, limk2 antibody, LIMK2 antibody, Limk2 antibody
    Background
    LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation through Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.Synonyms: EC=2.7.11.1, LIM domain kinase 2, LIMK-2, LIMK2
    Gene ID
    3985
    NCBI Accession
    NP_005560
    UniProt
    P53671
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