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LIMK2 antibody (C-Term)
LIMK2
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-LIMK2 Antibody
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Target
See all LIMK2 Antibodies
LIMK2
(LIM Domain Kinase 2 (LIMK2))
Binding Specificity
All epitopes for LIMK2 antibodies
C-Term
Reactivity
All reactivities for LIMK2 antibodies
Human, Mouse, Rat
Host
All hosts for LIMK2 antibodies
Rabbit
Clonality
All clonalities for LIMK2 antibodies
Polyclonal
Conjugate
All conjugates for LIMK2 antibodies
This LIMK2 antibody is un-conjugated
Application
All applications for LIMK2 antibodies
Western Blotting (WB)
Specificity
The antibody detects 70 kDa LIMK2 protein. It does not cross-react with LIMK1. The antibody recognizes ~35 kDa PHAP III.
Purification
Affinity Purified
Immunogen
Synthetic peptide corresponding to the C-terminus of human LIMK2.
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Discover our top product LIMK2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Western Blot: 1-4 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C/-80 °C
Storage Comment
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Target Details for LIMK2
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Target
LIMK2
(LIM Domain Kinase 2 (LIMK2))
Alternative Name
LIMK2 (LIMK2 Products )
Synonyms
xlimk2 antibody, zgc:91990 antibody, wu:fa97c09 antibody, wu:fk73e11 antibody, LIMK2 antibody, Limk2b antibody, Link2 antibody, LIMK antibody, 9430059K01 antibody, A930024P04Rik antibody, C85310 antibody, Limk2a antibody, LIM domain kinase 2 L homeolog antibody, LIM domain kinase 2 antibody, LIM motif-containing protein kinase 2 antibody, limk2.L antibody, limk2 antibody, LIMK2 antibody, Limk2 antibody
Background
LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation through Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.Synonyms: EC=2.7.11.1, LIM domain kinase 2, LIMK-2, LIMK2
Gene ID
3985
NCBI Accession
NP_005560
UniProt
P53671
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