HDAC9 antibody
Quick Overview for HDAC9 antibody (ABIN127248)
Target
See all HDAC9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- The antibody recognizes a ~110-140 kDa of HDAC-9. 75 kDa and a 60 kDa bands can also be detected in some tissue lysates.
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Purification
- Affinity purified
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Immunogen
- Synthetic peptide surrounding amino acid 25 of human HDAC-9.
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Application Notes
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The antibody can be used in Western blotting (0.5-4 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid Repeated freeze/defrost cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. For long-term storage, aliquot and freeze at -70 °C.
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- HDAC9 (Histone Deacetylase 9 (HDAC9))
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Alternative Name
- HDAC9
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Background
- HDAC family members have been divided into two classes. Class I of the HDACs comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93 % identity in amino acid sequence. Class II of the HDACs comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns.Synonyms: HD7B, HD9, HDAC7B, HDRP, Histone deacetylase 9, Histone deacetylase-related protein, KIAA0744, MEF2-interacting transcription repressor MITR, MITR
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Gene ID
- 9734
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NCBI Accession
- NP_001191073
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UniProt
- Q9UKV0
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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