CTLA4 antibody

Catalog No. ABIN135317

The Hamster Monoclonal anti-CTLA4 antibody is suitable to detect CTLA4 in samples from Mouse. It has been validated for FACS, ELISA and St.

Quick Overview for CTLA4 antibody (ABIN135317)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CTLA4 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Stimulation (St)

Clone: 1B8

Product Details anti-CTLA4 Antibody

Purpose: Hamster Anti-Mouse CD152-LE/AF

Specificity: Mouse CD152, Mr 33-37 kDa

Characteristics: Low Endotoxin/Azide Free Anti-Mouse CD152 antibody for use in flow cytometry, ELISA, and stimulation assays.

Endotoxin Level: Low Endotoxin

Immunogen: Extracellular portion of murine CTLA-4 fused to a murine IgG2a

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Alternative Name: CD152

Background: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer, and is relatively conserved among humans, mice and chickens.

Gene ID: 12477

UniProt: P09793

Pathways: Cancer Immune Checkpoints