CD79b antibody

Catalog No. ABIN135371

The Hamster Monoclonal anti-CD79b antibody is suitable to detect CD79b in samples from Mouse. It has been validated for FACS.

Quick Overview for CD79b antibody (ABIN135371)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD79b antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: HM79-12

Product Details anti-CD79b Antibody

Specificity: Mouse CD79b, Mr 37-39 kDa

Characteristics: Hamster Anti-Mouse CD79b-UNLB

Purification: Purified

Immunogen: CD79alpha/CD79beta heterodimers purified from mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231

Isotype: IgG

Application Details

Application Notes:

• Applications: FC - Quality tested , IP - Reported in literature , WB - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b

Background: Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an chain (CD79a/mb-1) and a chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.

Pathways: BCR Signaling