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IL2 Receptor beta antibody (FITC)

IL2RB Reactivity: Mouse FACS Host: Rat Monoclonal 5H4 FITC
Catalog No. ABIN135409
  • Target See all IL2 Receptor beta (IL2RB) Antibodies
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Reactivity
    • 92
    • 76
    • 16
    • 5
    • 1
    Mouse
    Host
    • 85
    • 24
    • 21
    Rat
    Clonality
    • 86
    • 43
    • 1
    Monoclonal
    Conjugate
    • 62
    • 9
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This IL2 Receptor beta antibody is conjugated to FITC
    Application
    • 73
    • 54
    • 38
    • 26
    • 26
    • 17
    • 14
    • 10
    • 10
    • 8
    • 7
    • 7
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Specificity
    Mouse CD122, 90-100 kDa
    Characteristics
    Rat Anti-Mouse CD122-FITC
    Immunogen
    Rat myeloma YB2/0 transfected with truncated IL-2Rbeta cDNA (YB2/0-mbetat-28)
    Clone
    5H4
    Isotype
    IgG2a
    Top Product
    Discover our top product IL2RB Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IP - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE and APC conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg in 1.0 mL of PBS/Sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Alternative Name
    CD122 (IL2RB Products)
    Synonyms
    IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
    Background
    The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the chain which binds IL-2 with low affinity, (ii) the chain that binds IL-2 with high affinity, and (ii) the common chain (C) that does not bind IL-2. The high affinity receptor complex is an α/β/γ heterotrimer with a kDa of 1.3 x 10-11 M.2 In mouse spleen, CD122 is expresed on 30 % of CD8+ cells and all NK cells, but < 1 % of B cells and CD4+ T lymphocytes. In the thymus, its expression is confined to CD4-CD8+ single positive and CD4-CD8- double negative cells. Cytoplasmic regions of the IL-2R chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes.
    Pathways
    JAK-STAT Signaling, Growth Factor Binding
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