Cytochrome C antibody (AA 71-75)

Catalog No. ABIN1355829

The Rabbit Polyclonal anti-Cytochrome C antibody (ABIN1355829) specifically detects Cytochrome C in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Cytochrome C antibody (AA 71-75) (ABIN1355829)

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytochrome C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cytochrome C Antibody

Binding Specificity: AA 71-75

Specificity: The antibody detects endogenous level of total Cytochrome C protein.

Immunogen: Peptide sequence around AA 71-75 (N-P-K-K-Y) derived from Human Cytochrome C.

Application Details

Application Notes: Western blotting: 1: 500-1: 1000

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C/-20 °C

Target Details for Cytochrome C

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Alternative Name: Cytochrome C

Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Molecular Weight: 14 kDa

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity