CD25 antibody (Biotin)

Catalog No. ABIN1383667

This Mouse Monoclonal antibody specifically detects CD25 in FACS. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for CD25 antibody (Biotin) (ABIN1383667)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD25 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: B-B10

Product Details anti-CD25 Antibody (Biotin)

Specificity: Recognises the Interleukin 2 Receptor a chain (IL-2 Ra), a 55 kDa protein

Purification: Ion exchange chromatography

Immunogen: PHA activated T cells,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Application Details

Application Notes: Use 10 μL to label 10^6 cells or 100 μL of whole blood

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Reconstitute with 1 mL deionised water.

Buffer: Lyophilisated in phosphate-buffered saline with 1 % BSA and 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Stable at +2-8°C for six months after reconstitution. For longer storage freeze aliquots.

References for anti-CD25 antibody (Biotin) (ABIN1383667)

Palmer, Farrokh-Siar, Maguire van Seventer, van Seventer: "IL-12 decreases activation-induced cell death in human naive Th cells costimulated by intercellular adhesion molecule-1. I. IL-12 alters caspase processing and inhibits enzyme function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 2, pp. 749-58, (2001) (PubMed).

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: CD25

Background: IL-2R α-Chain

Molecular Weight: 55 kDa

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation