CD25 antibody

Catalog No. ABIN1383668

The Mouse Monoclonal anti-CD25 antibody has been validated for FACS, IHC, ELISA and Func. It is suitable to detect CD25 in samples from Human. There is 1 publication available.

Quick Overview for CD25 antibody (ABIN1383668)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD25 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Functional Studies (Func)

Clone: B-F2

Product Details anti-CD25 Antibody

Specificity: Recognises the Interleukin 2 Receptor a chain (IL-2 Ra), a 55 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: PHA activated T cells,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits mixed lymphocyte culture

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-CD25 antibody (ABIN1383668)

Engert, Martin, Amlot, Wijdenes, Diehl, Thorpe: "Immunotoxins constructed with anti-CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent anti-tumour effects against human Hodgkin cells in vitro and solid Hodgkin tumours in mice." in: International journal of cancer. Journal international du cancer, Vol. 49, Issue 3, pp. 450-6, (1991) (PubMed).

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: CD25

Background: IL-2R α-Chain

Molecular Weight: 55 kDa

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation