FAS antibody

Catalog No. ABIN1383736

This Mouse Monoclonal antibody specifically detects FAS in IHC and FACS. It exhibits reactivity toward Human. It has been mentioned in 3+ publications

Quick Overview for FAS antibody (ABIN1383736)

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FAS antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: B-G27

Product Details anti-FAS Antibody

Specificity: Recognises the Fas, APO1 antigen, a 45 kDa protein

Purification: Ion exchange chromatography

Immunogen: Recombinant Fas antigen,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG2a, kappa

Application Details

Application Notes: Use 10 μL to label 10^6 cells or 100 μL of whole blood

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-FAS antibody (ABIN1383736)

Girard, Bisser, Courtioux, Vermot-Desroches, Bouteille, Wijdenes, Preudhomme, Jauberteau: "In vitro induction of microglial and endothelial cell apoptosis by cerebrospinal fluids from patients with human African trypanosomiasis." in: International journal for parasitology, Vol. 33, Issue 7, pp. 713-20, (2003) (PubMed).

Lautrette, Giraud, Vermot-Desroches, Preudhomme, Jauberteau: "Expression of a functional Fas death receptor by human foetal motoneurons." in: Neuroscience, Vol. 119, Issue 2, pp. 377-85, (2003) (PubMed).

Lautrette, Cardot, Vermot-Desroches, Wijdenes, Jauberteau, Battu: "Sedimentation field flow fractionation purification of immature neural cells from a human tumor neuroblastoma cell line." in: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Vol. 791, Issue 1-2, pp. 149-60, (2003) (PubMed).

Target Details for FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Alternative Name: CD95

Background: APO-1, FAS

Molecular Weight: 45 kDa

Pathways: p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity