DcR1 antibody

Catalog No. ABIN1383916

This Mouse Monoclonal antibody specifically detects DcR1 in FACS and Func. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for DcR1 antibody (ABIN1383916)

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DcR1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: B-D44

Product Details anti-DcR1 Antibody

Specificity: Recognises DcR1 (CD263), a 75.90 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant human TRAIL R3/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits TRAIL binding to TRAIL R3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-DcR1 antibody (ABIN1383916)

Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

Target Details for DcR1

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Alternative Name: TRAIL R3

Background: DcR1, TRAIL R3

Molecular Weight: 75.90 kDa

Pathways: Apoptosis