IL-8 antibody

Catalog No. ABIN1383947

There are 3+ publications for this product available. The Mouse Monoclonal anti-IL-8 antibody is suitable to detect IL-8 in samples from Human. It has been validated for ELISA, FACS and Func.

Quick Overview for IL-8 antibody (ABIN1383947)

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-8 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Functional Studies (Func)

Clone: B-K8

Product Details anti-IL-8 Antibody

Specificity: Recognises both natural and recombinant human IL-8

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant human IL-8,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits IL-8 induced chemotaxis of human neutrophils

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-IL-8 antibody (ABIN1383947)

Antonucci, Porcu, Timperi, Santini, Iannucci, Balsano: "Circulating Neutrophils of Nonalcoholic Steatohepatitis Patients Show an Activated Phenotype and Suppress T Lymphocytes Activity." in: Journal of immunology research, Vol. 2020, pp. 4570219, (2020) (PubMed).

Schruefer, Lutze, Schymeinsky, Walzog: "Human neutrophils promote angiogenesis by a paracrine feedforward mechanism involving endothelial interleukin-8." in: American journal of physiology. Heart and circulatory physiology, Vol. 288, Issue 3, pp. H1186-92, (2005) (PubMed).

Ulfman, Joosten, van der Linden, Lammers, Zwaginga, Koenderman: "IL-8 induces a transient arrest of rolling eosinophils on human endothelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 1, pp. 588-95, (2001) (PubMed).

Target Details for IL-8

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Alternative Name: IL-8

Background: CXCL8

Pathways: TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy