IL-15 antibody

Catalog No. ABIN1383961

Product Details anti-IL-15 Antibody

Target: IL-15 (IL15) (Interleukin 15 (IL15))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-15 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Functional Studies (Func)

Specificity: Recognises both natural and recombinant human IL-15

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant human IL-15,Myeloma X63/AG.8653 x Balb/c spleen cells

Clone: B-E29

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits IL-15 induced proliferation on Kit 225 cell line

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-IL-15 antibody (ABIN1383961)

Lebre, Jongbloed, Tas, Smeets, McInnes, Tak: "Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles." in: The American journal of pathology, Vol. 172, Issue 4, pp. 940-50, (2008) (PubMed).

Bernard, Harb, Mortier, Quéméner, Meloen, Vermot-Desroches, Wijdeness, van Dijken, Grötzinger, Slootstra, Plet, Jacques: "Identification of an interleukin-15alpha receptor-binding site on human interleukin-15." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24313-22, (2004) (PubMed).

Debili, Robin, Schiavon, Letestu, Pflumio, Mitjavila-Garcia, Coulombel, Vainchenker: "Different expression of CD41 on human lymphoid and myeloid progenitors from adults and neonates." in: Blood, Vol. 97, Issue 7, pp. 2023-30, (2001) (PubMed).

Suzuki, Nakajima, Watanabe, Kagami, Suto, Saito, Saito, Iwamoto: "Role of common cytokine receptor gamma chain (gamma(c))- and Jak3-dependent signaling in the proliferation and survival of murine mast cells." in: Blood, Vol. 96, Issue 6, pp. 2172-80, (2000) (PubMed).

Target Details for IL-15

Target: IL-15 (IL15) (Interleukin 15 (IL15))

Alternative Name: IL-15 (IL15 Products)

Synonyms: IL15 antibody, AI503618 antibody, IL-15 antibody, interleukin 15 antibody, IL15 antibody, Il15 antibody

Pathways: JAK-STAT Signaling, Glycosaminoglycan Metabolic Process