beta 2 Defensin antibody (AA 24-64)

Catalog No. ABIN1385259

Product Details anti-beta 2 Defensin Antibody

Target: beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))

Binding Specificity: AA 24-64

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta 2 Defensin antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human beta 2 Defensin

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-beta 2 Defensin antibody (ABIN1385259)

Al-Samadi, Salem, Ainola, Hietanen, Häyrinen-Immonen, Konttinen: "Increased beta 2 defensin in recurrent aphthous ulcer." in: Oral diseases, (2014) (PubMed).

Target Details for beta 2 Defensin

Target: beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))

Abstract: BD-2 Products

Synonyms: BD-2 antibody, BD-4 antibody, DEFB-4 antibody, hBD-4 antibody, BD2 antibody, DEFB2 antibody, defensin beta 2 antibody, defensin beta 104B antibody, beta defensin 2 antibody, Defb2 antibody, DEFB104B antibody, SBD2 antibody

Background:

Synonyms: BD-2, SAP1, DEFB2, DEFB4, HBD-2, DEFB-2, DEFB12, Beta-defensin 4A, Beta-defensin 2, Defensin, beta 2, Skin-antimicrobial peptide 1, DEFB4A

Background: Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways

Gene ID: 1673

UniProt: O15263