CTDNEP1A antibody (AA 121-200)

Catalog No. ABIN1385846

Product Details anti-CTDNEP1A Antibody

Target: CTDNEP1A (CTD Nuclear Envelope Phosphatase 1a (CTDNEP1A))

Binding Specificity: AA 121-200

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTDNEP1A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DULLARD

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CTDNEP1A

Target: CTDNEP1A (CTD Nuclear Envelope Phosphatase 1a (CTDNEP1A))

Alternative Name: DULLARD (CTDNEP1A Products)

Synonyms: Dullard antibody, 2610507E10Rik antibody, DULLARD antibody, HSA011916 antibody, NET56 antibody, dullard antibody, im:7137489 antibody, wu:fi48e07 antibody, zgc:92207 antibody, ctdnep1 antibody, dullard-b antibody, net56 antibody, CTD nuclear envelope phosphatase 1 antibody, CTD nuclear envelope phosphatase 1a antibody, CTD nuclear envelope phosphatase 1 L homeolog antibody, Ctdnep1 antibody, CTDNEP1 antibody, ctdnep1a antibody, ctdnep1.L antibody

Background:

Synonyms: Dullard homolog, HSA 011916, NET 56 antibodySerine threonine protein phosphatase dullard, CNEP1_HUMAN.

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. Dullard, also known as NET56, is a 244 amino acid single-pass membrane protein that localizes to both the nucleus and the endoplasmic reticulum and contains one FCP1 homology domain. Functioning as a serine/threonine phosphatase, Dullard catalyses the dephosphorylation of target proteins and is thought to be required for proper nuclear membrane morphology. Human Dullard shares 92 % sequence identity with its zebrafish counterpart, suggesting a conserved role between species.