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BCAS1 antibody (AA 542-584)

BCAS1 Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386549
  • Target See all BCAS1 Antibodies
    BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))
    Binding Specificity
    • 15
    • 14
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 542-584
    Reactivity
    • 40
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 38
    • 2
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCAS1 antibody is un-conjugated
    Application
    • 40
    • 18
    • 12
    • 12
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Predicted Reactivity
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BCAS1
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Kaji, Maki, Ueda, Ishimoto, Inoue, Yasuda, Sawamura, Hikawa, Ayaki, Yamakado, Takahashi: "BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy." in: Acta neuropathologica communications, Vol. 8, Issue 1, pp. 120, (2021) (PubMed).

  • Target
    BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))
    Alternative Name
    BCAS1/NABC1 (BCAS1 Products)
    Synonyms
    AIBC1 antibody, NABC1 antibody, 2210416M21Rik antibody, 9030223A09Rik antibody, AI841227 antibody, Band83 antibody, Pmes-2 antibody, BCAS1 antibody, MGC152145 antibody, breast carcinoma amplified sequence 1 antibody, BCAS1 antibody, Bcas1 antibody
    Background

    Synonyms: AIBC 1, AIBC1, Amplied and overexpressed in breast cancer, BCAS 1, BCAS1, BCAS1_HUMAN, Breast carcinoma amplied sequence 1, Breast carcinoma-amplied sequence 1, Novel amplied in breast cancer 1.

    Background: NaBC1 is a protein found amplified in most breast carcinoma forms. It is expressed primarily as a cytoplasmic, detergent-stable homodimer that has a tendency to interact with DYNLL1 (PIN) and DYNLL2. Breast tumor lines that exhibit 20q13.2 gene amplification express much higher levels of the protein as compared to the levels found in other breast cancer lines that do not overexpress the NaBC1 mRNA. However, this upregulation does not affect growth rate or anchoring abilities of a cell, indicating the oncogenic properties of NaBC1 differ from that of other oncogenes.

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