BCAS1 antibody (C-Term)

Catalog No. ABIN6991283

Product Details anti-BCAS1 Antibody

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Binding Specificity: AA 460-510, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: BCAS1 Antibody is affinity chromatography purified via peptide column.

Immunogen: BCAS1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human BCAS1. The immunogen is located within amino acids 460 - 510 of BCAS1.

Isotype: IgG

Application Details

Application Notes: BCAS1 antibody can be used for detection of BCAS1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: BCAS1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: BCAS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for BCAS1

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Alternative Name: BCAS1 (BCAS1 Products)

Synonyms: AIBC1 antibody, NABC1 antibody, 2210416M21Rik antibody, 9030223A09Rik antibody, AI841227 antibody, Band83 antibody, Pmes-2 antibody, BCAS1 antibody, MGC152145 antibody, breast carcinoma amplified sequence 1 antibody, BCAS1 antibody, Bcas1 antibody

Background: BCAS1 Antibody: BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein, BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.

Gene ID: 8537

UniProt: O75363