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FBXW5 antibody

FBXW5 Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386926
  • Target See all FBXW5 Antibodies
    FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
    Reactivity
    • 33
    • 16
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 31
    • 2
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXW5 antibody is un-conjugated
    Application
    • 29
    • 12
    • 11
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FBXW5
    Isotype
    IgG
    Top Product
    Discover our top product FBXW5 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
    Alternative Name
    FBXW5 (FBXW5 Products)
    Synonyms
    Fbw5 antibody, AI159739 antibody, F-box and WD repeat domain containing 5 antibody, F-box and WD-40 domain protein 5 antibody, FBXW5 antibody, Fbxw5 antibody
    Background

    Synonyms: F box and WD 40 domain containing protein 5, F box and WD repeat domain containing 5, FBW5, FBXW5_HUMAN.

    Background: FBXW5 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW5 contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.

    Gene ID
    54461
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