ZNF521 antibody (AA 851-950)

Catalog No. ABIN1387594

Product Details anti-ZNF521 Antibody

Target: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Binding Specificity: AA 851-950

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF521 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EHZF/ZNF521

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZNF521

Target: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Alternative Name: ZNF521 (ZNF521 Products)

Background:

Synonyms: Early hematopoietic zinc finger, Early hematopoietic zinc finger protein, EHZF, Evi3, LYST-interacting protein 3, MGC142182, Zfp521, Zinc finger protein 521, ZN521_HUMAN, Znf521.

Background: Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage, this interaction preventing EBF1 to bind DNA and activate target genes.

Gene ID: 25925