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ZNF521 antibody (N-Term)

ZNF521 Reactivity: Human ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991692
  • Target See all ZNF521 Antibodies
    ZNF521 (Zinc Finger Protein 521 (ZNF521))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 7
    • 2
    • 1
    Human
    Host
    • 9
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This ZNF521 antibody is un-conjugated
    Application
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    ZNF521 antibody is human specific.
    Purification
    ZNF521 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    ZNF521 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZNF521. The immunogen is located within the first 50 amino acids of ZNF521.
    Isotype
    IgG
    Top Product
    Discover our top product ZNF521 Primary Antibody
  • Application Notes
    ZNF521 antibody can be used for detection of ZNF521 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ZNF521 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    ZNF521 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    ZNF521 (Zinc Finger Protein 521 (ZNF521))
    Alternative Name
    ZNF521 (ZNF521 Products)
    Synonyms
    Znf521 antibody, EHZF antibody, Evi3 antibody, B930086A16Rik antibody, zinc finger protein 521 antibody, zinc finger protein 521 S homeolog antibody, Zfp521 antibody, ZNF521 antibody, znf521.S antibody
    Background
    ZNF521 Antibody: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
    Molecular Weight
    Predicted: 144 kDa

    Observed: 145 kDa
    Gene ID
    25925
    NCBI Accession
    NP_056276
    UniProt
    Q96K83
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