HS1BP3 antibody (AA 51-130)

Catalog No. ABIN1387640

The Rabbit Polyclonal anti-HS1BP3 antibody is suitable to detect HS1BP3 in samples from Human. It has been validated for ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC.

Quick Overview for HS1BP3 antibody (AA 51-130) (ABIN1387640)

Target: HS1BP3 (HCLS1 Binding Protein 3 (HS1BP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS1BP3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-HS1BP3 Antibody

Binding Specificity: AA 51-130

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HS1BP3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HS1BP3

Target: HS1BP3 (HCLS1 Binding Protein 3 (HS1BP3))

Alternative Name: HS1BP3

Background:

Synonyms: ETM2, FLJ14249, H1BP3_HUMAN, HCLS1 binding protein 3, HCLS1-binding protein 3, HS1 binding protein 3, HS1 BP3, HS1-BP3, HS1-binding protein 3, Hs1bp3, HSP1BP-3.

Background: HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1?s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation.