EPH Receptor B1 antibody (pTyr968) (AbBy Fluor® 647)

Catalog No. ABIN1388628

This anti-EPH Receptor B1 antibody is a Rabbit Polyclonal antibody detecting EPH Receptor B1 in WB, IF (cc) and IF (p). Suitable for Mouse and Rat.

Quick Overview for EPH Receptor B1 antibody (pTyr968) (AbBy Fluor® 647) (ABIN1388628)

Target: EPH Receptor B1 (EPHB1)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B1 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-EPH Receptor B1 Antibody (AbBy Fluor® 647)

Binding Specificity: pTyr968

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human EphB1 around the phosphorylation site of Tyr968

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EPH Receptor B1

Target: EPH Receptor B1 (EPHB1)

Alternative Name: Eph receptor B1

Background:

Synonyms: Eph receptor B1phospho Y968, EphB1phospho Y968Cek 6, Elkh, Eph tyrosine kinase 2, EPH2, EphB1, Ephrin receptor Eph B1 precursor, Ephrin type B receptor 1, HEK 6, NET, Neuronally expressed EPH related tyrosine kinase, Tyrosine protein kinase receptor EPH 2.

Background: EphB1, previously known as Elk (eph like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class. EphB1 is expressed predominately in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, EphB1 signals regulation of cell attachment and cell to cell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.

Gene ID: 2047

Pathways: RTK Signaling