GBA antibody (AbBy Fluor® 350)

Catalog No. ABIN1393269

The AbBy Fluor® 350-conjugated Rabbit Polyclonal anti-GBA antibody (ABIN1393269) specifically detects GBA in WB and IF. The antibody is reactive with Human samples.

Quick Overview for GBA antibody (AbBy Fluor® 350) (ABIN1393269)

Target: GBA (Glucosidase, Beta, Acid (GBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GBA Antibody (AbBy Fluor® 350)

Purpose: GBA Polyclonal Antibody, AbBy Fluor-350 Conjugated

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GBA

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000), IF(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Alternative Name: GBA/Acid beta-Glucosidase

Background:

Synonyms: Glucosidase beta, Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45 , Gba protein, GBA1, GC antibody GCase, GCB, GLCM_HUMAN, GLUC, Glucocerebrosidase (alt.), Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta, acid (includes glucosylceramidase), Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase.

Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

Gene ID: 2629

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process