Serotonin Receptor 1E antibody (AA 1-120) (AbBy Fluor® 647)

Catalog No. ABIN1394850

This anti-Serotonin Receptor 1E antibody is a Rabbit Polyclonal antibody detecting Serotonin Receptor 1E in IF (cc) and IF (p). Suitable for Human.

Quick Overview for Serotonin Receptor 1E antibody (AA 1-120) (AbBy Fluor® 647) (ABIN1394850)

Target: Serotonin Receptor 1E (HTR1E)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 1E antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Serotonin Receptor 1E Antibody (AbBy Fluor® 647)

Binding Specificity: AA 1-120

Predicted Reactivity: Human,Cow,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT1E Receptor/SR-1E

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Serotonin Receptor 1E

Target: Serotonin Receptor 1E (HTR1E)

Alternative Name: 5HT1E Receptor/SR-1E

Background:

Synonyms: 5 hydroxytryptamine serotonin receptor 1E, 5 hydroxytryptamine serotonin receptor 1E G protein coupled, 5 hydroxytryptamine 1E receptor, 5-HT-1E, 5-hydroxytryptamine receptor 1E, HTR1E, S31, Serotonin receptor 1E, 5HT1E_HUMAN.

Background: The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Pathways: JAK-STAT Signaling, cAMP Metabolic Process