DENND1B antibody (AA 241-350) (Biotin)

Catalog No. ABIN1398091

This Rabbit Polyclonal antibody specifically detects DENND1B in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for DENND1B antibody (AA 241-350) (Biotin) (ABIN1398091)

Target: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND1B antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DENND1B Antibody (Biotin)

Binding Specificity: AA 241-350

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DENND1B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DENND1B

Target: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Alternative Name: DENND1B

Background:

Synonyms: C1ORF18, C1orf218, Chromosome 1 open reading frame 218, Connecdenn 2, DEN1B_HUMAN, DENN domain containing protein 1B, DENN domain-containing protein 1B, DENN MADD domain containing 1B, DENND1B, DKFZp547O0715, FAM31B, Family with sequence similarity 31 member B, FLJ20054, FLJ21179, FLJ33888, MGC103810, MGC27044, Protein FAM31B

Background: Guanine nucleotide exchange factor (GEF) for RAB35. May function as a clathrin-associated sorting protein for RAB35, whereby during clathrin-mediated endocytosis, binds the AP-2 complex and inactived RAB35, then activates RAB35 for its subsequent function at endosomes.Tissue specificity:Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T cells as compared with naive T cells.

Gene ID: 163486

UniProt: Q6P3S1