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POLB antibody (AA 55-160) (Biotin)

This Rabbit Polyclonal antibody specifically detects POLB in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.
Catalog No. ABIN1399555

Quick Overview for POLB antibody (AA 55-160) (Biotin) (ABIN1399555)

Target

See all POLB Antibodies
POLB (Polymerase (DNA Directed), beta (POLB))

Reactivity

  • 46
  • 42
  • 27
  • 9
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Mouse

Host

  • 56
  • 4
Rabbit

Clonality

  • 49
  • 10
Polyclonal

Conjugate

  • 29
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This POLB antibody is conjugated to Biotin

Application

  • 38
  • 21
  • 18
  • 14
  • 13
  • 5
  • 5
  • 5
  • 4
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

    • 14
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 55-160

    Cross-Reactivity

    Mouse

    Predicted Reactivity

    Human,Rat,Dog,Cow,Pig,Horse,Chicken

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DNA Polymerase beta

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C for 12 months.

    Expiry Date

    12 months
  • Target

    POLB (Polymerase (DNA Directed), beta (POLB))

    Alternative Name

    DNA Polymerase beta

    Background

    Synonyms: DNA polymerase beta, POLB

    Background: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

    Gene ID

    5423

    UniProt

    P06746

    Pathways

    DNA Damage Repair
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