RHOB antibody (AA 101-196) (HRP)

Catalog No. ABIN1407416

The Rabbit Polyclonal anti-RHOB antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect RHOB in samples from Human.

Quick Overview for RHOB antibody (AA 101-196) (HRP) (ABIN1407416)

Target: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOB antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RHOB Antibody (HRP)

Binding Specificity: AA 101-196

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Rho B

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RHOB

Target: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Alternative Name: Rho B

Background:

Synonyms: Rh -related GTP binding protein RhoB, Rh -related GTP binding protein RhoC, RHOH6, Transforming protein RhoA, AA017882 antibody Aplysia ras related homolog 9 RhoC, ARH9, ARHA, ARHB, ARHC, H6, MST081, MSTP08, Oncogene RHO H9, rhoC GTPase, Ras homolog 9 RhoC, Ras homolog gene family, member A, Ras homolog gene family, member B, Ras homolog gene family, member C, Rho related GTP binding protein RhoC, RHO12, RHOB, RHOC, RHOH9, RP11-426L16.4, Small GTP binding protein RhoC, H9, Rho related GTP binding protein RhoB, ARH12, ARH6, H12.RHOB_HUMAN

Background: The Rho proteins interact directly with protein kinases which are likely to serve as downstream effector targets of the activated GTPase. The Rho family of GTPases are involved in the regulation of the actin skeleton. Activation of Rho to the GTP bound state promotes formation of stress fibers and is required for the formation and maintenance of focal adhesions. Pathways stimulated by cytokines, hormones and various forms of stress utilize p21 proteins of the Rho family. Possible mediators for these responses include protein kinase such as p120PKN, and p150 ROKa/Rho-A kinase, myosin light chain (MLC) phosphatase and PIP 5-kinase.

Gene ID: 388