ZNF318 antibody (AA 1077-1125) (HRP)

Catalog No. ABIN1409030

The Rabbit Polyclonal anti-ZNF318 antibody has been validated for WB, IHC (p), ELISA and IHC (fro). It is suitable to detect ZNF318 in samples from Human, Mouse and Rat.

Quick Overview for ZNF318 antibody (AA 1077-1125) (HRP) (ABIN1409030)

Target: ZNF318 (Znf318) (Zinc Finger Protein 318 (Znf318))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF318 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ZNF318 Antibody (HRP)

Binding Specificity: AA 1077-1125

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF318

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZNF318

Target: ZNF318 (Znf318) (Zinc Finger Protein 318 (Znf318))

Alternative Name: ZNF318

Background:

Synonyms: Endocrine Regulatory Protein, HGNC13578, HRIHFB2436, ZFP318, Zinc Finger Protein 318, ZN318_HUMAN.

Background: ZNF318 is a 2279 amino acid endocrine regulatory protein that localizes to the nucleus. Highly expressed in testis, ovaries and kidneys, ZNF318 is a co-repressor of androgen receptor (AR)-mediated transcriptional activation and is thought to regulate transcription during spermatogenesis. ZNF318 interacts with the N-terminal domain of AR and contains two matrin-type zinc fingers. Two isoforms of ZNF318, designated TZF and TZF-L, are produced due to alternative splicing events. Each of these splice variants are thought to have unique roles in transcriptional regulation. While the TZF isoform functions as a repressor of AR-mediated transcriptional activation, the TZF-L isoform is thought to enhance AR-mediated transcriptional activation.

Gene ID: 24149

Pathways: SARS-CoV-2 Protein Interactome