NPY5R antibody (AA 1-100) (HRP)

Catalog No. ABIN1409654

The Rabbit Polyclonal anti-NPY5R antibody has been validated for WB and ELISA. It is suitable to detect NPY5R in samples from Human and Mouse.

Quick Overview for NPY5R antibody (AA 1-100) (HRP) (ABIN1409654)

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY5R antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-NPY5R Antibody (HRP)

Binding Specificity: AA 1-100

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NPY5R

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NPY5R

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Alternative Name: NPY5R

Background:

Synonyms: Neuropeptide Y receptor type 5, Neuropeptide Y receptor Y5, NPY 5R, NPY R5, NPY Y5, NPY Y5 receptor, NPY-Y5 receptor, NPY5 R, NPY5-R, NPY5R, NPY5R_HUMAN, NPYR 5, NPYR5, NPYY 5, NPYY5, NPYY5-R, Y5 receptor.

Background: Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35 % overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31.

Pathways: Feeding Behaviour