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DISP2 antibody (AA 1101-1200) (Cy5)

DISP2 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN1410052
  • Target See all DISP2 Antibodies
    DISP2 (Dispatched Homolog 2 (DISP2))
    Binding Specificity
    • 14
    • 2
    • 2
    • 1
    • 1
    AA 1101-1200
    Reactivity
    • 18
    • 2
    • 2
    Human
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DISP2 antibody is conjugated to Cy5
    Application
    • 12
    • 12
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DISP2
    Isotype
    IgG
    Top Product
    Discover our top product DISP2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    DISP2 (Dispatched Homolog 2 (DISP2))
    Alternative Name
    DISP2 (DISP2 Products)
    Synonyms
    DISP2 antibody, DISPB antibody, HsT16908 antibody, AI840597 antibody, B230210L08Rik antibody, DispB antibody, mKIAA1742 antibody, dispatched RND transporter family member 2 antibody, dispatched RND tramsporter family member 2 antibody, dispatched homolog 2 (Drosophila) antibody, DISP2 antibody, Disp2 antibody
    Background

    Synonyms: DISPB, HsT16908, Protein dispatched homolog 2, DISP2, KIAA1742

    Background: DISP2 is the second of three known homologs of the D.melanogaster protein Dispatched. It is a multitransmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants. At least two isoforms of DISP2 are known to exist.

    Gene ID
    85455
    UniProt
    A7MBM2
    Pathways
    Hedgehog Signaling
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