CHRM4 antibody (AA 1-31) (Cy5)

Catalog No. ABIN1412452

This Rabbit Polyclonal antibody specifically detects CHRM4 in FACS, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for CHRM4 antibody (AA 1-31) (Cy5) (ABIN1412452)

Target: CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM4 antibody is conjugated to Cy5

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CHRM4 Antibody (Cy5)

Binding Specificity: AA 1-31

Purpose: CHRM4 Polyclonal Antibody, Cy5 Conjugated

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHRM4/mAChR M4

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CHRM4

Target: CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))

Alternative Name: CHRM4/mAChR M4

Background:

Synonyms: HM4, M4R, Muscarinic acetylcholine receptor M4, CHRM4

Background: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.

Gene ID: 1132

UniProt: P08173

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Synaptic Membrane