Serotonin Receptor 4 antibody (AA 161-270) (HRP)

Catalog No. ABIN1412786

The Rabbit Polyclonal anti-Serotonin Receptor 4 antibody has been validated for WB, ELISA and IHC (fro). It is suitable to detect Serotonin Receptor 4 in samples from Human.

Quick Overview for Serotonin Receptor 4 antibody (AA 161-270) (HRP) (ABIN1412786)

Target: Serotonin Receptor 4 (HTR4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Serotonin Receptor 4 Antibody (HRP)

Binding Specificity: AA 161-270

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT4 Receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Serotonin Receptor 4

Target: Serotonin Receptor 4 (HTR4)

Alternative Name: 5HT4 Receptor

Background:

Synonyms: 5 HT 4, 5 HT4, 5 HT4R, 5 hydroxytryptamine 4 receptor, 5 hydroxytryptamine receptor 4, 5 hydroxytryptamine serotonin receptor 4, 5 hydroxytryptamine4 receptor, 5-HT-4, 5-ht4, 5-HT4R, 5H4, 5HT 4, 5HT4, 5ht4 receptor, 5HT4R, Cardiac 5 HT4 receptor, HTR 4, HTR4, serotonin 4 receptor, Serotonin 5 HT4 receptor, serotonin 5-ht-4 receptor, serotonin 5-ht-4a. Serotonin receptor 4, 5HT4R_HUMAN.

Background: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]

Gene ID: 3360

UniProt: Q13639

Pathways: JAK-STAT Signaling, cAMP Metabolic Process, S100 Proteins